The research projects in the Han Lab are aimed at elucidating the molecular mechanisms of genetic diseases of skeletal and cardiac muscle such as muscular dystrophy and cardiomyopathy. By understanding the molecular mechanisms of these genetic disorders, we hope to shed light on the design of novel therapeutic strategies for these devastating diseases.
1) Dysferlin forms a dimer in vitro and in vivo Read more
2) Complement ablation ameliorates disease progression in dysferlin-null mice Read more
3) Protective mechanism of alpha-dystroglycan for the sarcolemma integrity Read more
4) The role of dysferlin-mediated membrane repair in the heart Read more