International Journal

2023

● Machine-learning enhancement of urine dipstick tests for chronic kidney disease detection
Eun Chan Jang, Young Min Park, Hyun Wook Han, Christopher Seungkyu Lee, Eun Seok Kang, Yu Ho Lee, Sang Min Nam
Journal of the American Medical Informatics Association

● Relationship between drug targets and drug-signature networks: a network-based genome-wide landscape
Chae Won Lee, Sung Min Kim, Soonok Sa, Myunghee Hong, Sang-Min Nam & Hyun Wook Han
BMC Medical Genomics

● COVID-19 Vaccination Is Not Associated with Psychiatric Adverse Events: A Meta-Analysis
Sang-Eun Lee, Sung-Ryul Shim, Jung-Hae Youn, Hyun-Wook Han
Vaccines

2022

● Using Natural Language Processing to Identify Low Back Pain in Imaging Reports
Yeji Kim†, Chanyoung Song†, Gyuseon Song, Sol Bi Kim, Hyun-Wook Han*, Inbo Han*
Applied Sciences.

● 감염병 위기 대응을 위한 소셜 데이터 수집 및 적재 엔진 기반 신뢰도 분석 시스템 개발
정두영, 이상준, 민경일, 정석송, 한현욱.
(사)한국빅데이터학회

● FGM-Based Remote Intervention for Adults With Type 1 Diabetes: The FRIEND Randomized Clinical Trial
Jinju Lee, Myeong Hoon Lee, Jiyun Park, Kyung-Soo Kim, Soo-Kyung Kim, Yong-Wook Cho, Hyun Wook Han*, Young Shin Song*.
Frontiers in endocrinology

● Development and validation of a nonalcoholic fatty liver disease-based self-diagnosis tool for diabetes
Hye Jun Kim, Yohwan Lim, Sung Soo Yoon, Sang Jun Lee, Myeong Hoon Lee, Hyewon Park, Sun Jae Park, Seogsong Jeong, Hyun Wook Han.
Annals of translational medicine

● Safety of COVID-19 Vaccines among Patients with Type 2 Diabetes Mellitus: Real-World Data Analysis
Hye Jun Kim, Sang Jun Lee, Soonok Sa, Jung Ho Bae, Gyuseon Song, Chae Won Lee, Ju Hee Kim, Sung Ryul Shim, Myunghee Hong, Hyun Wook Han
Diabetes and Metabolism Journal

● Natural Language Processing for Assessing Quality Indicators in Free-Text Colonoscopy and Pathology Reports: Development and Usability Study
Bae JH, Han HW, Yang SY, Song G, Sa S, Chung GE, Seo JY, Jin EH, Kim H, An D
JMIR Med Inform

● Effects of meteorological factors and air pollutants on the incidence of COVID-19 in South Korea
Shim SR, Kim HJ, Hong M, Kwon SK, Kim JH, Lee SJ, Lee SW, Han HW
Environ Res

● Diagnostic Performance of Antigen Rapid Diagnostic Tests, Chest Computed Tomography, and Lung Point-of-Care-Ultrasonography for SARS-CoV-2 Compared with RT-PCR Testing: A Systematic Review and Network Meta-Analysis
Shim SR, Kim SJ, Hong M, Lee J, Kang MG, Han HW
Diagnostics (Basel)

● Natural Language Processing for Information Extraction of Gastric Diseases and Its Application in Large-Scale Clinical Research
Song G, Chung SJ, Seo JY, Yang SY, Jin EH, Chung GE, Shim SR, Sa S, Hong MS, Kim KH, Jang E, Lee CW, Bae JH, Han HW
J Clin Med

● Adverse Events and Safety Profile of the COVID-19 Vaccines in Adolescents: Safety Monitoring for Adverse Events Using Real-World Data
Lee CW, Sa S, Hong M, Kim J, Shim SR, Han HW
Vaccines (Basel)

● Factor Analysis Affecting Degree of Depression in Family Caregivers of Patients with Spinal Cord Injury: A Cross-Sectional Pilot Study
Su-Jin Lee†, Myung-Gwan Kim, Jung hee Kim, Yu-Sun Minm Chul-Hyung Kim, Kyoung-Tae Kim*, Wong-Moon Hwang*.
Int. J. Environ. Res. Public Health

● Physical Activity and Quality of Life in Adult Men and Women with Distorted Perception of Weight Status-Nationwide Surveys (KNHANES 2016-2018)
Su-Jin Lee†, Min-Gyu Lim, Jung hee Kim, Chulyong Park, YoungJi Ko, Myung-Gwan Kim, Chul-Hyun Kim, Aeryoung Kim, Jong-Moon Hwang*
Int. J. Environ. Res. Public Health

● Risk factors influencing COVID-19 mortality rate in OECD countries: A cross-sectional study
Su-Jin Lee†, Myung-Gwan Kim†, Jung Hee Kim, Chulyong Park, Aeryoung Kim*, Jong-Moon Hwang*
Medicine.

● Incident and recurrent herpes zoster for first-line bDMARD and tsDMARD users in seropositive rheumatoid arthritis patients: a nationwide cohort study
Jeong S†, Choi S†, Park SM, Kim J, Ghang B*, Lee EY*
Arthritis Res Ther

● Association of the presence of allergic disease with subsequent risk of liver cancer in a nationwide retrospective cohort among Koreans
Kim JA†, Park SJ, Choi S, Chang J, Jeong S, C Ahn J, Lee G, Son JS*, Park SM*
Sci Rep

● Health-Screening-Based Chronic Obstructive Pulmonary Disease and Its Effect on Cardiovascular Disease Risk
Lee SJ†, Yoon SS†, Lee MH, Kim HJ, Lim Y, Park H, Park SJ, Jeong S*, Han HW*
J Clin Med

● Association between Proton Pump Inhibitor Use and Risk of Hepatocellular Carcinoma: A Korean Nationally Representative Cohort Study
Kim S†, Jeong S, Park SJ, Chang J, Choi S, Cho Y, Ahn JC, Lee G, Son JS, Park SM*
J Clin Med

● Sex-separated NAFLD/NASH Scores May Improve Predictive Performance
Jeong S†, Kim HJ, Han HW
Clin Gastroenterol Hepatol

● Association of non-alcoholic fatty liver disease with incident dementia later in life among elder adults
Jeong S†, Oh YH, Choi S, Chang J, Kim SM, Son JS, Lee G, Ahn JC, Lee DH, Koo BK, Kim W, Park SM*
Clin Mol Hepatol

● Maternal disease factors associated with neonatal jaundice : a case-control study
Youngjae Yu†, Jinwha Choi†, Myeong Hoon Lee, KangHyun Kim, Hyun Mee Ryu & Hyun Wook Han*
BMC Pregnancy and Childbirth

● Personalized Prediction of Kidney Function Decline and Network Analysis of the Risk Factors after Kidney Transplantation Using Nationwide Cohort Data
Moongi Simon Hong†, Yu-Ho Lee†, Jin-Min Kong, Oh-Jung Kwon, Cheol-Woong Jung, Jaeseok Yang, Myoung-Soo Kim, Hyun-Wook Han*, Sang-Min Nam*
Journal of Clinical Medicine

● The Safety of mRNA-1273, BNT162b2, and JNJ-78436735 COVID-19 Vaccines: Safety Monitoring for Adverse Events Using Real-World Data
Soonok Sa†, Chae Won Lee†, Sung Ryul Shim, Hyounggyoon Yoo, Jinwha, Ju Hee Kim, Kiwon Lee, Myunghee Hong* and Hyun Wook Han*
Vaccines



2021

● Discovery of Depression-Associated Factors From a Nationwide Population-Based Survey: Epidemiological Study Using Machine Learning and Network Analysis
Sang Min Nam†, Thomas A Peterson†, Kyoung Yul Seo, Hyun Wook Han, Jee In Kang*
JMIR



2020

● Epidemiological Characterization of a Directed and Weighted Disease Network: Network Analysis Using One Million Cohort Data
Kyungmin Ko†, Chae Won Lee†, Sangmin Nam†, Song Vogue Ahn, Chi Yong Ban, Jungho Bae, Jongman Yoo, Jungmin Park, Hyun Wook Han*
JMIR



2019

● Explanatory Model of Dry Eye Disease Using Health and Nutrition Examinations: Machine Learning and Network-Based Factor Analysis From a National Survey
Sang Min Nam†, Thomas A. Peterson†, Atul J. Butte, Kyoung Yul Seo, and Hyun Wook Han*
JMIR Medical Informatics

● The Fever Coach Mobile App for Participatory Influenza Surveillance in Children: Usability Study
Myeonchan Kim†, Sehyo Yun†, Seyun Chang, Yuseob Jeong, Soon Ok Sa, Hyun Wook Han*
JMIR mHealth and Uhealth



2018

● LINCS L1000 dataset-based repositioning of CGP-60474 as a highly potent anti-endotoxemic agent
Hyun-Wook Han, Soojung Hahn, Hye Yun Jeong, Joo-Hyun Jee, Myoung-Ok Nam, Han Kyung Kim, Dong Hyeon Lee, So-Young Lee, Dong Kyu Choi, Ji Hoon Yu, Sang-Hyun Min & Jongman Yoo
Scientific Reports (First)

● Computer-Aided Multi-Target Management of Emergent Alzheimer's Disease
Hyunjo Kim, Hyun Wook Han
Bioinformation (Correspondence)



2017

● Network-based analysis of diagnosis progression patterns using claims data
Eugen Jeong, Kyung-min Go, Seungbin Oh, Hyun Wook Han
Scientific Reports (Correspondence)

● Organoid-based epithelial to mesenchymal transition (OEMT) model: from intestinal fibrosis perspective
Soojung Hahn, Myeong-Ok Nam, Jung Hyun Noh, Dong Hyeon Lee, Hyun Wook Han, Duk Hwan Kim, Ki Baik Hahm, Sung Pyo Hong, Jun-Hwan Yoo, Jongman Yoo
Scientific Reports



2015

● Functional Analysis of the Molecular Interactions of TATA Box-Containing Genes and Essential Genes
SangHun Bae, Hyun Wook Han, Jisook Moon
PLOS One (Co-first)



2013

● Yin and Yang of disease genes and death genes between reciprocally scale-free biological network
Hyun Wook Han, Junghun Ohn, Jisook Moon, Juhan Kim
Nucleic Acids Research

● Genome-wide characterization of the relationship between essential and TATA-containing genes
Hyun Wook Han, Sang Hun Bae, Yun Hwa Jung, Ju Han Kim, Jisook Moon
FEBS Letters



Domestic Journal

● 헬스케어 빅데이터 유통을 위한 블록체인기술 활성화 방안
유형원, 이은솔, 고우균, 한호성, 한현욱
한국빅데이터학회 (교신저자)



Proceeding & Poster

● The causal network of human diseases using medical claim data
Eugene Jeong, Kyungmin Go, Hyun Wook Han
TBC 2016

● Compliance of Korean patients with inflammatory bowel disease to colonoscopy
Jehuk Choi, Hyun Wook Han
TBC 2016

● A Disease Network representing combinatorial risk ratio calculations in a Large sample Cohort
Kyungmin Go, Eugene Jeong, Hyun Wookk Han
TBC 2016

● Bioinformatics-based analysis of sepsis and CMap public microarra data
Seoungbin Oh, Hyun Wook Han

● Network-based characterization of relationship between drug-targets and perturbed genes.
Eurim Lee, Seungbin Oh, Hyun Wook Han
KOSMI 2017 spring

● 국민건강보험공단 표본코호트 DB를 이용한 질환 네트워크 구축 및 분석
정유진, 한현욱
대한의료정보학회 2017 봄

● Detecting Influenza Epidemics Using Self-reported Data Through Mobile App (FeverCoach)
Myeongchan Kim, Sehyo Yune, Hyun Wook Han
JMIR

● Mapping Between GNL code and ATC code of Prescribed Drugs in NHIS Cohort data
Kang Hyun Kim, Hyun Wook Han
KOSMI 2019, Spring

● A case-control study on maternal risk factors for neonatal jaundice
Young Jea Yoo, Hyun Wook Han
KOSMI 2019, Spring

● Gene set enrichment analysis를 통한 약물 타겟 유전자와 DEG 간의 특성 규명
Chea Woon Lee, Hyun Wook Han
KOSMI 2019, Spring

● Prospective Statistical Research of Neonatal Jaundice by NHIS Cohort Data
Jea Ho Choi, Hyun Wook Han
KOSMI 2019, Spring



Book

● 이것이 헬스케어 빅데이터이다 (클라우드나인출판사), 2018년 1월



Our Award

● Construction of Korean Drug Usage Pattern Network Using Claim Data
Kang Hyun Kim, Gyu Seon Song, Jung Ho Bae, Hyun Wook Han
KOSMI 2019, fall, 대한의료정보학회 우수연재상

● KODA: 블록체인 기반 헬스케어 데이터거래소
Kang Hyun Kim, JeongYong Kang, Moon Gi Hong, Gyu Seon Song, Dong Wuk An, Hyeong Won Yu, Hyun Wook Han
KITS 2020, Spring, 한국생산기술원장상(최우수상)